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321 SNPs From Major IBD SNP Studies' Comparison

         EVenn.png                               PDF (1).png

           The Venn and UpSet Diagram show the shared SNPs between different major IBD SNP studies,321 unique IBD SNPs were identified after comparison.


IBD aoosiated SNPs


IDRS_IDGeneChrSNP_indexPhenotypeOR_phenotype_lociPvalue_phenotype_loci
1rs9726836CCNL21chr1:1388944:G:AIBD0.9099187223.085E-13
2rs1886730TNFRSF141chr1:2557169:T:CUC0.9106469486.001E-16
3rs225131ERRFI11chr1:8035426:T:CIBD0.8966407491.032E-23
4rs6426833RNF1861chr1:19845367:G:AUC1.2419714551.484E-74
5rs34963268ZBTB401chr1:22384384:G:CIBD0.8776564932.918E-25
6rs7525903RUNX31chr1:24968082:G:ACD0.9045660081.367E-13
7rs140466198PTAFR1chr1:28131939:C:TCD1.2980978491.052E-08
8rs12138864PHC21chr1:33337547:C:TUC1.0667322463.983E-08
9rs6687307PLPP31chr1:56454342:C:TUC0.9182367724.516E-08
10rs7543380ATG4C1chr1:62768997:T:ACD0.9282074748.587E-09
11rs11581607IL23R1chr1:67242007:G:AIBD0.5474960673.79E-123
12rs7552319CHORDC1P51chr1:70567336:A:CUC0.9301587586.661E-09
13rs17391694GIPC21chr1:78157942:C:TCD0.9080098980.00004047
14rs11165441TGFBR31chr1:91758790:G:AIBD0.9348211984.452E-08
15rs3767964DR11chr1:93349933:T:CCD1.0875201362.186E-10
16rs11583043DPH51chr1:101000498:C:TIBD1.0352055440.001448
17rs17572009SLC25A241chr1:108112400:A:CIBD1.0657726196.486E-10
18rs2476601PTPN221chr1:113834946:A:GCD1.2189623945.575E-15
19rs116062645NOTCH21chr1:119982857:G:TIBD1.2278933782.628E-09
20rs1336900HORMAD11chr1:150706557:G:AIBD0.9262602844.11E-15
21rs11204894RORC1chr1:151820698:G:TIBD0.9068302522.621E-17
22rs3766920SHC11chr1:154962487:G:AIBD1.3922205631.146E-13
23rs34687326SLAMF81chr1:159830120:G:ACD0.8761657443.816E-07
24rs6658353FCGR2A1chr1:161499264:G:CUC0.8530816633.294E-39
25rs6025F51chr1:169549811:C:TIBD0.8504412050.000009384
26rs10912488AIMP1P21chr1:172877652:A:GCD1.1818724475.529E-24
27rs72709461ABL21chr1:179134699:T:CCD1.1250190852.139E-10
28rs10798069PLA2G4A1chr1:186906327:G:TCD0.9440274830.0000068
29rs10801047-1chr1:191590226:A:TIBD0.9817682470.2773
30rs2224873DENND1B1chr1:197676319:T:AIBD1.099219081.416E-15
31rs74359027PTPRC1chr1:198689168:TA:TIBD0.9043851121.296E-12
32rs2816980NR5A21chr1:200108907:G:TUC1.1591650953.251E-12
33rs35730213INAVA1chr1:200905101:G:CIBD0.8645034355.836E-34
34rs11240504CDK181chr1:205516162:T:AUC1.076699132.374E-08
35rs3024495IL101chr1:206769068:C:TIBD1.2296136325.168E-55
36rs2073486IRF61chr1:209802870:G:AIBD1.0554846021.664E-08
37rs11582528PSEN21chr1:226819948:C:TUC0.9176859951.546E-08
38rs10910476IRF2BP21chr1:234599210:C:TIBD1.0661990137.057E-11
39rs11894081LINC012482chr2:5523876:G:TIBD0.9973036420.7914
40rs7578575DNMT3A2chr2:25265950:T:AIBD1.0843708971.543E-15
41rs1260326GCKR2chr2:27508073:T:CCD0.9026684122.283E-16
42rs12478126FOSL22chr2:28423081:C:TCD1.1108216872.962E-16
43rs78487399THADA2chr2:43582208:G:CCD1.1991344444.178E-13
44rs67927699PUS102chr2:60960280:G:CIBD1.140423864.075E-37
45rs6759003RN7SL51P2chr2:62332070:T:CCD0.9278362654.756E-09
46rs1370394SPRED22chr2:65453176:T:GIBD1.0656660478.554E-11
47rs1882348IL18R12chr2:102368211:T:AIBD0.9056521381.595E-26
48rs12475901NCK22chr2:105777237:G:ACD0.9719994890.07981
49rs72837826BCL2L112chr2:111175424:G:TUC1.1261446671.467E-08
50rs55678466BIN12chr2:127092119:T:CIBD1.0544296452.486E-08
51rs56862595TEX412chr2:144784617:T:CIBD0.8935079921.821E-09
52rs4664304PLA2R12chr2:159937497:A:GIBD0.9789252430.02197
53rs2111485FAP2chr2:162254026:A:GIBD0.9373486263.386E-11
54rs151175749PDK12chr2:172559679:C:GCD1.1247941049.575E-07
55rs2124440ITGA42chr2:181463487:G:AIBD0.9212719593.98E-17
56rs2595392ITGAV2chr2:186665389:C:GIBD0.901045076.228E-09
57rs142152795NAB12chr2:190704810:C:TCD1.4286072232.107E-09
58rs6738825PLCL12chr2:198032171:A:GCD0.9136570473.212E-11
59rs34119476AC019330.12chr2:198719455:A:GUC1.1099333851.898E-19
60rs3769684CD282chr2:203720036:T:CIBD0.9026684121.552E-12
61rs11690316CXCR12chr2:218152739:A:GIBD1.0833954024.56E-18
62rs4973341CCL202chr2:227795646:C:TIBD1.0793942461.802E-13
63rs13385151SP1402chr2:230251261:C:TCD1.1667242082.195E-16
64rs12692254ATG16L12chr2:233252565:A:TCD1.2435870682.191E-63
65rs34236350GPR352chr2:240628909:C:TIBD1.1836465867.706E-54
66rs115622046BOK2chr2:241546197:C:TIBD0.9203511475.932E-08
67rs35320439GAL3ST22chr2:241797926:T:CIBD1.0303514940.007419
68rs73180609SATB1-AS13chr3:18770480:A:CCD1.1188484659.125E-11
69rs6770038TGFBR23chr3:30608835:T:CIBD1.0736885894.36E-08
70rs113010081CCRL23chr3:46415921:T:CUC1.1431641642.466E-11
71rs1131095APEH3chr3:49676792:T:CIBD1.1773898541.932E-55
72rs138317798RPL293chr3:52013158:TGGA:TUC1.1448801971.429E-08
73rs35783750RFT13chr3:53100847:T:CCD0.9080098981.215E-13
74rs2593855FOXP13chr3:71126344:C:TIBD0.9298797526.683E-10
75rs503734IMPG23chr3:101304904:A:GCD0.9383802778.339E-07
76rs616597NFKBIZ3chr3:101850882:A:CIBD1.0592911942.534E-08
77rs1317244CD2003chr3:112334718:G:ACD1.0912239980.0001383
78rs6763931ZBTB383chr3:141383991:G:ACD1.1176184084.423E-19
79rs56116661LPP3chr3:188683372:C:TIBD0.9032101763.725E-15
80rs16844401HGFAC4chr4:3447925:G:AIBD1.1342821681.117E-12
81rs4692386LINC023574chr4:26130739:T:CIBD1.0266488970.008608
82rs61797472ARAP24chr4:36061370:A:GIBD1.0650268396.313E-11
83rs73243351LINC025134chr4:38333446:G:AIBD1.1582381332.856E-22
84rs11734570KLF34chr4:38586832:G:ACD1.0549569920.00003854
85rs7438704SLAIN24chr4:48361228:A:GIBD1.0137942750.1408
86rs2472649CXCL54chr4:73991991:A:GUC1.0653463950.00007314
87rs13107325SLC39A84chr4:102267552:C:TCD1.2225025157.18E-13
88rs2903386TET24chr4:105178652:T:CIBD0.9321141448.193E-14
89rs147909357IL24chr4:122523884:G:GTIBD1.0862158956.177E-19
90rs4081846CEP725chr5:573904:G:AUC0.8951177552.438E-08
91rs3776414DAP5chr5:10689450:T:GIBD1.0749777895.673E-14
92rs3194051IL7R5chr5:35876172:A:GIBD1.037900580.0007485
93rs395157OSMR5chr5:38867630:C:TIBD1.080474189.881E-17
94rs7725052TTC335chr5:40487168:C:TIBD1.1342821681.399E-40
95rs10065637ANKRD555chr5:56143024:C:TCD0.9107380170.000001055
96rs4703855PTCD25chr5:72398072:C:TCD0.9442163070.0000123
97rs6870798TMEM1745chr5:73248171:C:TCD0.9176859951.122E-09
98rs10041920SERINC55chr5:80229545:A:GIBD0.9484748552.458E-08
99rs6873866ERAP25chr5:96912106:T:CCD0.8944913913.134E-16
100rs7705924LINC004925chr5:102611094:A:GIBD1.0471791240.07348
101rs341295EPB41L4A5chr5:112513193:C:TIBD1.0516916894.933E-08
102rs2188962SLC22A55chr5:132435113:C:TIBD1.1336018032.854E-32
103rs254560PITX15chr5:135107916:G:AUC1.0916605751.73E-13
104rs181826NDFIP15chr5:142146492:C:AIBD1.0741181514.652E-14
105rs59672579ARHGAP265chr5:142866576:C:TIBD0.907283781.483E-10
106rs1000113IRGM5chr5:150860514:C:TIBD1.1689430921.437E-32
107rs1363232TIMD45chr5:156956411:A:GIBD0.943178242.271E-08
108rs755374IL12B5chr5:159402286:C:TIBD1.1829366115.212E-67
109rs2101594STK105chr5:172151212:C:TIBD1.0535864394.867E-08
110rs564349ERGIC15chr5:172897975:G:AIBD0.9290432372.979E-13
111rs359457CPEB45chr5:173852839:C:TCD1.0520072440.00004336
112rs10051765RGS145chr5:177372991:T:CIBD1.0782075651.238E-14
113rs55982276PHYKPL5chr5:178217126:CAG:CUC0.8656280218.757E-09
114rs77688705DUSP226chr6:246629:G:AIBD0.864589894.708E-09
115rs17309827SLC22A236chr6:3433084:T:GCD0.943178240.000003623
116rs17119RNU6-793P6chr6:14719265:G:AIBD1.0983400565.009E-13
117rs181635615ID46chr6:19787512:G:AUC0.7361657379.414E-09
118rs2328546CDKAL16chr6:20657114:T:CIBD1.1063872754.861E-19
119rs4710973AL031767.26chr6:21385471:T:CIBD0.9233009887.852E-16
120rs9271511HLA-DQA16chr6:32621706:G:AUC0.7073002651.38E-158
121rs67289879TAF86chr6:42039665:C:TCD1.1038455083.299E-07
122rs1044690TMEM151B6chr6:44277504:G:CCD0.9168604494.306E-08
123rs943689BACH26chr6:90274316:C:TCD0.9066489041.567E-09
124rs9480634ATG56chr6:106020611:C:TIBD0.9222859154.246E-17
125rs73534586TRAF3IP26chr6:111594960:G:AUC1.2143391261.263E-13
126rs2858829DSE6chr6:116447754:A:GUC1.0684403849.116E-09
127rs210648DCBLD16chr6:117522909:A:GIBD1.0597149962.823E-09
128rs9482770RSPO36chr6:127121947:T:CCD1.0855643616.193E-11
129rs9491891PTPRK6chr6:127956006:A:GCD1.0968034560.000007333
130rs6933404LINC025396chr6:137638098:T:CUC1.1480903547.593E-19
131rs12191421PHACTR26chr6:143570283:A:GIBD0.8919903192.862E-09
132rs7758080TAB26chr6:149255943:A:GCD1.085347277.647E-10
133rs212408TAGAP6chr6:159049210:G:TCD0.9027586831.33E-12
134rs6939196RNASET26chr6:166965500:C:TIBD0.9012252973.4E-24
135rs74572369ADAP17chr7:944282:T:ACD0.794851486.695E-14
136rs2260230GNA127chr7:2783352:T:AUC0.899064959.807E-17
137rs748670681TNRC187chr7:5397122:C:TIBD2.2761831888.99E-93
138rs2034400LINC028897chr7:17559004:T:GUC1.0777763685.824E-09
139rs76380568ABCB57chr7:20542073:T:CIBD0.8766039371.139E-10
140rs10486483SKAP27chr7:26852821:G:ACD1.0812307760.000000525
141rs11495981JAZF17chr7:28137682:C:TCD1.0968034567.074E-10
142rs73120731ELMO17chr7:37417880:A:GCD1.1435071655.286E-13
143rs1990134GLI37chr7:41935319:C:TUC1.0803661381.129E-09
144rs6976037EPS15P17chr7:46834111:A:TUC1.0717576885.224E-09
145rs4917129IKZF17chr7:50283578:T:CIBD1.0866504686.351E-19
146rs117026326GTF2I7chr7:74711703:C:TIBD1.2026169811.818E-11
147rs144341967SMURF17chr7:99150512:T:GIBD1.1541913866.787E-09
148rs1734907EPO7chr7:100717894:A:GCD0.9105558885.129E-07
149rs4380874SLC26A37chr7:107839870:T:CUC0.8720574281.643E-28
150rs38902ST77chr7:117249664:G:AUC0.9395070091.777E-07
151rs3757387IRF57chr7:128936032:T:CUC1.1093785571.503E-17
152rs243500CUL17chr7:148742273:G:CIBD0.9363181092.802E-11
153rs17057051PTK2B8chr8:27370037:A:GCD0.9388495840.000005247
154rs77535993IDI1P28chr8:48207903:G:TUC0.9011351795.497E-09
155rs12677663SBSPON8chr8:73095112:G:TIBD1.0267515670.007324
156rs389848RIPK28chr8:89784739:T:GCD0.9630017980.08451
157rs2721933TRPS18chr8:115614948:T:CUC1.0727227042.002E-08
158rs4380956TRIB18chr8:125516832:G:AIBD1.0775608343.229E-15
159rs938649LINC008248chr8:128540288:G:TCD0.8417266171.553E-14
160rs1991866CCDC268chr8:129611859:G:CIBD0.9488543212.231E-08
161rs438041DENND38chr8:141164479:C:TIBD1.0230619070.01809
162rs79832570SPATC18chr8:144042819:T:CCD1.2253175075.708E-11
163rs682251DOCK89chr9:271455:T:CCD0.9233933231.557E-08
164rs36051895JAK29chr9:4981866:G:TIBD1.1455673311.698E-43
165rs9408254FAM205A9chr9:34736161:A:GCD1.0914422640.00003379
166rs11142085SPATA31C29chr9:88081422:G:AIBD1.06162420.02628
167rs4743820AUH9chr9:91166134:C:TUC1.0680130937.95E-08
168rs10992396IPPK9chr9:92674850:A:GIBD1.0863245221.384E-12
169rs56211063TNFSF159chr9:114823617:G:CIBD1.3879113623.04E-89
170rs4986790TLR49chr9:117713024:A:GCD1.1420215710.000006454


图文展示
IDRS_IDGeneChrSNP_indexPhenotypeOR_phenotype_lociPvalue_phenotype_loci
171rs8176719ABO9chr9:133257521:T:TCCD1.0841540441.298E-09
172rs3812565SNAPC49chr9:136378050:T:CIBD1.1306582673.222E-37
173rs12722489IL2RA10chr10:6060049:C:TIBD0.9162188722.428E-11
174rs4748198PRKCQ10chr10:6607973:C:TIBD0.9244096146.844E-12
175rs7911117ABI110chr10:26890667:T:GIBD0.9605012460.003316
176rs7898978MAP3K810chr10:30410871:T:CIBD0.9245945151.481E-15
177rs12764283CREM10chr10:35241532:G:AIBD1.1015298657.711E-24
178rs769009FRMPD210chr10:48182406:G:TCD0.9232086637.339E-09
179rs2790211IPMK10chr10:58243611:T:CIBD0.9206272944.702E-14
180rs10761659ALDH7A1P410chr10:62685804:A:GIBD1.1529224733.896E-51
181rs2688607PLAU10chr10:73903978:A:GCD1.1226590245.962E-17
182rs1250566ZMIZ110chr10:79286696:G:AIBD0.8984358251.274E-28
183rs1870148TSPAN1410chr10:80511585:G:ACD1.1371214218.519E-12
184rs11203002CH25H10chr10:89146767:C:GUC0.8913661442.985E-12
185rs7918084KIF1110chr10:92669710:C:TIBD1.0719720612.015E-12
186rs11188950LCOR10chr10:96860106:T:GUC1.1740977733.425E-11
187rs4409764NKX2-310chr10:99524480:T:GIBD0.850186113.442E-72
188rs113369211BTRC10chr10:101436625:AATAGATAGATAGATAG:AATAGATAGATAGATAGATAGUC0.8164415131.803E-08
189rs11591780MFSD13A10chr10:102465559:C:GUC1.0709006255.073E-09
190rs10884966DUSP510chr10:110425838:G:ACD1.1475164524.65E-22
191rs111456533FAM53B10chr10:124750812:G:ACD0.9197071270.000002249
192rs10734105TCERG1L10chr10:131373856:G:AIBD1.0090406220.3891
193rs907613TNNI211chr11:1853062:G:AIBD1.076699134.547E-13
194rs9645621NUCB211chr11:17311651:A:GIBD1.0635368454.204E-08
195rs77531520PRR5L11chr11:36410895:C:TIBD1.1420215711.444E-08
196rs181068528OR5AR111chr11:56679337:A:TIBD1.800924247.592E-11
197rs11229030SLC43A311chr11:57435536:C:TIBD0.9984012790.8671
198rs10896794LPXN11chr11:58571651:T:CUC0.9142968312.388E-08
199rs11230563CD611chr11:61008737:C:TIBD0.933793463.114E-11
200rs174564FADS111chr11:61820833:A:GIBD1.0788546838.356E-16
201rs1783521CCDC88B11chr11:64338819:T:CCD0.9092820021.146E-10
202rs2303385EFEMP211chr11:65873091:G:ACD0.9270942933.347E-08
203rs11235667FCHSD211chr11:73152652:A:GCD1.2214027580.000001277
204rs71040008EMSY11chr11:76587581:G:GTIBD1.1568490811.397E-44
205rs6592362TMEM13511chr11:87414396:A:GIBD0.9876765630.2357
206rs79608745LINC0274811chr11:91270280:A:GIBD1.0128822710.5916
207rs483905MAML211chr11:96290263:G:AUC1.0554846020.00001633
208rs561722NXPE111chr11:114516108:C:TUC0.9119227479.262E-15
209rs141340254MPZL211chr11:118273990:A:GCD0.6210771314.658E-08
210rs3176905CXCR511chr11:118884921:T:CIBD0.9551374710.0008656
211rs11221332ETS111chr11:128511079:C:TIBD1.0643880151.661E-07
212rs4020660LTBR12chr12:6402491:G:ACD1.09570724.095E-11
213rs11612508DUSP1612chr12:12504579:A:GUC1.0525333790.0001059
214rs181198871-12chr12:37910758:G:AIBD1.6446046150.000006364
215rs75913487RNU6-713P12chr12:40562563:T:CCD1.6354205696.067E-20
216rs11168249HDAC712chr12:47814585:T:CUC1.0717576886.256E-08
217rs199762200ERBB312chr12:56076060:G:AIBD0.8839100287.181E-09
218rs1558746IFNG12chr12:68111348:G:AIBD1.1445367841.342E-26
219rs61576454LYZ12chr12:69348988:AT:AIBD0.9230240394.304E-08
220rs4762271ELK312chr12:96137691:A:GCD1.1008691456.282E-11
221rs117121174ATP2A212chr12:110259525:G:ACD0.7440105981.346E-10
222rs11066188HECTD412chr12:112172910:G:AIBD1.0805822327.248E-13
223rs113281820MIR4472-212chr12:116408331:C:TIBD1.0435204030.0005682
224rs11064881CIT12chr12:119709120:G:AIBD1.1165013487.322E-09
225rs17085007RPS21P813chr13:26957130:T:CUC1.1913653473.793E-35
226rs17630801ELF113chr13:40965681:A:CIBD1.2107015682.355E-20
227rs9525562DGKH13chr13:42037531:C:ACD0.9136570471.389E-11
228rs1535903FAM216B13chr13:42797254:C:TUC0.9256121281.042E-08
229rs1373904LACC113chr13:43901262:A:GCD1.1755075363.631E-30
230rs2026029FNDC3A13chr13:49021195:A:GIBD1.0544296453.976E-08
231rs184429843NEK513chr13:52062509:C:TIBD1.7088147474.069E-09
232rs9585037UBAC213chr13:99348586:A:TIBD0.9153031114.92E-12
233rs743228NFKBIA14chr14:35390868:C:TCD0.9122875893.51E-12
234rs4902367MAX14chr14:65142694:C:GUC1.0793942462.786E-09
235rs194746ZFP36L114chr14:68816170:C:TIBD1.080474183.462E-17
236rs1569328FOS14chr14:75275048:C:TIBD0.9151200683.092E-13
237rs4462528GALC14chr14:87959953:T:CIBD1.1568490815.484E-24
238rs11627111ELK2AP14chr14:105686797:A:GIBD0.8702280284.29E-08
239rs147034755RASGRP115chr15:38617263:A:CCD1.1092676252.631E-09
240rs28374715CHP115chr15:41271752:A:GUC0.9367863850.00001154
241rs11071559RORA15chr15:60777789:C:TIBD0.9215483821.196E-09
242rs56375023SMAD315chr15:67156025:G:AIBD1.1238946281.518E-23
243rs1864239ST2015chr15:79913012:A:GIBD0.9797086960.3611
244rs12440543ABHD17C15chr15:80675204:T:CIBD0.9389434741.476E-09
245rs71407313CRTC315chr15:90600362:C:TIBD0.8889627011.992E-13
246rs7170683LRRK115chr15:100948377:T:CCD1.0737959644.795E-08
247rs191241541PKD116chr16:2117121:C:TIBD1.851322042.797E-09
248rs11641184LITAF16chr16:11610795:C:AIBD1.0850217142.14E-18
249rs59790099PRKCB16chr16:23857964:G:AUC0.911011282.09E-11
250rs201121732IL21R16chr16:27384341:C:CTUC1.2523227162.532E-08
251rs4787458IL2716chr16:28519966:A:GIBD1.0915514141.962E-18
252rs77948921CD2BP216chr16:30328432:G:AUC1.090896689.435E-12
253rs5743289NOD216chr16:50722863:C:TCD1.5240937947.56E-113
254rs6499186CDH316chr16:68626662:C:TUC1.0924250053.36E-09
255rs8055490TMEM170A16chr16:75463237:C:TIBD0.949803652.754E-08
256rs9938250WWOX16chr16:78768798:A:GIBD0.9314618922.71E-08
257rs187975120CDYL216chr16:80804680:G:TIBD1.2645293533.5E-09
258rs11548656PLCG216chr16:81883307:A:GIBD0.8234108441.183E-11
259rs76640285CDH1316chr16:82844608:GA:GCD1.0986696074.477E-08
260rs16940202IRF816chr16:85980635:T:CIBD1.1320158711.239E-25
261rs16946807CRK17chr17:1453285:C:ACD1.0740107442.451E-08
262rs415704CLEC10A17chr17:7074375:C:TIBD0.9430839273.66E-08
263rs2948542KSR117chr17:27529460:A:GCD1.1041767121.631E-14
264rs4795894CCL717chr17:34264425:C:TIBD0.9152115858.333E-19
265rs11658993IKZF317chr17:39784555:C:TIBD1.1326952841.116E-41
266rs9911533SMARCE117chr17:40619224:C:TUC1.0965841171.944E-14
267rs12601611STAT317chr17:42345810:C:TIBD0.8752900178.995E-40
268rs4598971ITGB317chr17:47259971:T:GCD0.9862947830.3134
269rs1470831SKAP117chr17:48268286:C:TIBD0.9293219923.478E-10
270rs3853824C17orf6717chr17:56803632:T:CCD1.059926960.00002073
271rs1292053TUBD117chr17:59886176:A:GIBD1.0673724787.43E-13
272rs9904398METTL2A17chr17:62449865:G:AIBD0.9616545390.07062
273rs8072795SLC39A1117chr17:72643045:G:AIBD0.8965510892.737E-13
274rs17736589CYTH117chr17:78741036:A:GUC1.0700442470.00001419
275rs116885423PVALEF17chr17:81183249:G:TUC1.5690965381.88E-08
276rs663411SMCHD118chr18:2734945:C:GIBD1.0570690171.78E-08
277rs547268PTPN218chr18:12823057:G:TIBD0.8901191041.907E-25
278rs16978179SETBP118chr18:44806588:T:CCD1.1817542651.248E-13
279rs138863186CTIF18chr18:48863700:C:CTTGIBD0.8170132236.111E-09
280rs9635956ELAC118chr18:50977537:G:AIBD1.0573861851.609E-08
281rs9319943GRP18chr18:59212595:T:CCD1.0731518790.000004512
282rs727088CD22618chr18:69863203:G:AIBD0.9630017980.00004358
283rs7236492NFATC118chr18:79460616:C:TIBD0.9472426390.0001207
284rs11669443SBNO219chr19:1109216:G:AIBD1.108713139.956E-21
285rs2240751MFSD1219chr19:3548233:A:GCD1.1432784865.957E-08
286rs12720356TYK219chr19:10359299:A:CIBD1.1585856572.891E-16
287rs172032ELL19chr19:18522945:T:CCD1.080474187.33E-09
288rs138636798SLC7A1019chr19:33260220:T:TCIBD1.1432784865.514E-24
289rs587259LSM14A19chr19:34165501:C:TIBD0.984521050.1492
290rs1644682ZNF56819chr19:36991870:G:ACD0.9277434865.578E-09
291rs2604913COQ8B19chr19:40712706:G:AIBD0.9414820473.692E-10
292rs55665939PPP5C19chr19:46346189:A:GCD0.9039330332.554E-09
293rs646327FUT219chr19:48706594:A:GCD1.1090457934.941E-12
294rs34587409RPS919chr19:54203491:G:ACD1.0918789297.128E-11
295rs11672983FCAR19chr19:54871595:G:AUC1.0748702971.82E-09
296rs4256018FERMT120chr20:6113242:T:GIBD1.0611996361.856E-08
297rs6042824MACROD220chr20:14618543:C:ACD0.9142968311.095E-08
298rs875519NOL4L20chr20:32503432:T:CIBD1.0687609642.368E-10
299rs4911259DNMT3B20chr20:32788476:T:GIBD1.0382119970.0002266
300rs6088765MMP2420chr20:35211477:T:GIBD1.0184684710.04851
301rs6071961AL009050.120chr20:40169106:T:GIBD1.0676927372.808E-08
302rs17181845ZHX320chr20:41301389:T:GIBD1.0760533041.949E-08
303rs6017342HNF4A20chr20:44436388:A:CUC1.2020158235.295E-46
304rs1883832CD4020chr20:46118343:T:CCD0.9044755551.274E-13
305rs913678LINC0127120chr20:50338887:T:CIBD0.9409173273.897E-10
306rs259964ZNF83120chr20:59249254:A:GIBD0.9320209371.011E-12
307rs6062496TNFRSF6B20chr20:63697746:G:AIBD1.1507342.26E-44
308rs7277261CYCSP4221chr21:15448734:C:TIBD0.8656280217.027E-40
309rs2284553IFNGR221chr21:33404389:A:GCD1.1158316491.844E-17
310rs2836882PSMG121chr21:39094644:G:AIBD0.8669274374.848E-40
311rs13047030TRAPPC1021chr21:44057275:A:GIBD0.9249644279.169E-10
312rs12158299UBE2L322chr22:21625295:C:TIBD1.1172831732.995E-27
313rs5761654CRYBA422chr22:26641724:G:CIBD0.9480007363.549E-08
314rs1003342HORMAD222chr22:30174033:A:GIBD0.9288574471.591E-15
315rs4821382HMGXB422chr22:35242122:G:CUC1.0873026543.103E-10
316rs2413430CSF2RB22chr22:36908468:A:TCD0.8207801419.728E-17
317rs9611131PDGFB22chr22:39266475:T:CIBD0.8253894035.027E-38
318rs727563ACO222chr22:41471373:C:TIBD0.9788273550.03804
319rs5771192IL17REL22chr22:50003556:A:CUC1.1067192411.118E-17
320rs2427870VGLL1XchrX:136581905:C:TIBD0.9068302525.667E-13


Ref:Liu Z, Liu R, Gao H, Jung S, Gao X, Sun R, Liu X, Kim Y, Lee HS, Kawai Y, Nagasaki M, Umeno J, Tokunaga K, Kinouchi Y, Masamune A, Shi W, Shen C, Guo Z, Yuan K; FinnGen; International Inflammatory Bowel Disease Genetics Consortium; Chinese Inflammatory Bowel Disease Genetics Consortium; Zhu S, Li D, Liu J, Ge T, Cho J, Daly MJ, McGovern DPB, Ye BD, Song K, Kakuta Y, Li M, Huang H. Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries. Nat Genet. 2023 May;55(5):796-806. doi: 10.1038/s41588-023-01384-0. Epub 2023 May 8.



IBD associated SNPs


ID
Chr
Position (bp)
SNP
P value
PMID
Phenotype
Genes in locus
1
1
1247494
rs12103
8e-13
23128233
IBD
SCNN1D,CPSF3L,TAS1R3,RP4-758J18.2,MRPL20,UBE2J2,ACAP3,PUSL1,GLTPD1,DVL1,MXRA8,CCNL2,AURKAIP1
2
1
2501338
rs10797432
3e-12
23128233
UC
FAM213B,MMEL1,TNFRSF14
3
1
8022197
rs3766606
8.84e-18
26192919
IBD
VAMP3,UTS2,PARK7,ERRFI1,PER3,TNFRSF9,CAMTA1
4
1
20171860
rs6426833
8.56e-69
FM
UC,IBD
RNF186,OTUD3
5
1
22702231
rs12568930
1e-17
23128233
IBD
.
6
1
63049593
rs1748195
7.13e-08
26192919
CD
ANGPTL3,AL138847.1,DOCK7,USP1
7
1
67707690
rs11581607
8.76e-175
FM
IBD
INSL5,MIER1,IL12RB2,TCTEX1D1,WDR78,SLC35D1,C1orf141,IL23R,SERBP1,SGIP1
8
1
70995562
rs2651244
2e-08
23128233
IBD
.
9
1
78623626
rs17391694
2.62e-09
26192919
CD
FUBP1,DNAJB4,NEXN,GIPC2
10
1
92554283
rs34856868
9.8e-09
26192919
IBD
BRDT,EPHX4,BTBD8,KIAA1107,C1orf146,GLMN,GFI1,RPAP2,EVI5,TGFBR3
11
1
101466054
rs11583043
1.92e-06
26192919
IBD
AC093157.1,EXTL2,SLC30A7,DPH5
12
1
114165757
rs2636006
2.34e-42
FM
IBD
DCLRE1B,RSBN1,PTPN22,AP4B1,MAGI3,BCL2L15,PHTF1
13
1
120451190
rs3897478
2e-11
23128233
CD
ADAM30,NOTCH2
14
1
151801680
rs4845604
1.21e-17
26192919
IBD
RORC
15
1
155230131
rs3180018
2e-13
21102463
CD
SLC50A1,DPM3,KRTCAP2,MUC1,MTX1,SCAMP3,RUSC1,RXFP4,SSR2,EFNA1,RP11-201K10.3,TRIM46,THBS3,GBA,FAM189B,CLK2,HCN3,PKLR,FDPS,YY1AP1,DAP3,GON4L,RIT1,KIAA0907,UBQLN4,EFNA3,EFNA3,ASH1L,MSTO1,SYT11,ARHGEF2
16
1
159799910
rs34687326
1.06e-08
NOVEL
CD
SLAMF8
17
1
160856964
rs4656958
2.05e-11
26192919
IBD
ITLN1,ITLN2
18
1
161479745
rs1801274
2e-38
23128233
IBD
HSPA6,FCGR3A,FCGR3B,FCGR2B,FCGR2A
19
1
169519049
rs6025
2.51e-08
26192919
IBD
CCDC181,SLC19A2,F5,SELP,SELL,SELE,ATP1B1,NME7,BLZF1,C1orf112
20
1
172853460
rs7517810
4.53e-22
26192919
CD
.
21
1
186875459
rs10798069
2.49e-07
26192919
IBD
PLA2G4A
22
1
191559356
rs10801047
3e-08
17554261
CD
.
23
1
197701279
rs2488397
5.64e-18
FM
IBD
CRB1,DENND1B
24
1
198598663
rs7555082
2.54e-09
26192919
IBD
PTPRC
25
1
200101920
rs2816958
2e-17
23128233
IBD
NR5A2
26
1
200877562
rs7554511
3.2e-44
26192919
IBD
C1orf106,KIF21B,CACNA1S
27
1
206939904
rs3024505
2.99e-50
26192919
IBD
IL10
28
1
209970610
rs59043219
1.09e-08
NOVEL
IBD
DIEXF,IRF6
29
2
5664008
rs11894081
4e-09
23266558
CD
.
30
2
25097644
rs13407913
1.69e-20
26192919
IBD
POMC,ADCY3,DNAJC27,EFR3B,DNMT3A
31
2
27730940
rs1260326
1.74e-21
26192919
CD
SNX17,ZNF513,KRTCAP3,FNDC4,PPM1G,IFT172,GCKR,NRBP1
32
2
28614794
rs925255
3e-15
23128233
IBD
FOSL2
33
2
43806918
rs10495903
2e-14
21102463
IBD
ZFP36L2,THADA
34
2
61204856
rs7608910
2.6e-36
26192919
IBD
PUS10
35
2
62552321
rs11679753
2.65e-12
FM
CD
.
36
2
65667272
rs6740462
5.59e-12
26192919
IBD
SPRED2
37
2
102939036
rs13001325
2.51e-23
FM
IBD
IL1RL2,IL1RL1,IL18R1,IL18RAP,SLC9A4,IL1R2,IL1R1
38
2
145492382
rs11681525
4.08e-11
26192919
CD
.
39
2
160794008
rs4664304
2.61e-08
26192919
IBD
LY75-CD302,LY75,PLA2R1
40
2
163110536
rs2111485
4.6e-09
26192919
IBD
GCG,IFIH1,FAP,GCA,KCNH7
41
2
182308352
rs6740847
1.22e-13
NOVEL
IBD
ITGA4
42
2
187576378
rs144344067
1.29e-08
NOVEL
IBD
ITGAV,FAM171B
43
2
191931464
rs1517352
3.87e-14
26192919
IBD
STAT4
44
2
198896895
rs6738825
4e-09
21102463
UC
MARS2,HSPE1-MOB4,MOB4,BOLL,RFTN2,AC011997.1,PLCL1
45
2
199560757
rs17229679
7.05e-20
FM
UC
PLCL1,SATB2
46
2
204592021
rs3116494
5.11e-07
26192919
IBD
CD28
47
2
219151218
rs2382817
1.13e-13
26192919
IBD
CXCR2,CXCR1,GPBAR1,AAMP,RUFY4,ARPC2,PNKD,TMBIM1
48
2
228660112
rs111781203
2.16e-10
26192919
IBD
.
49
2
228670476
rs1811711
6.09e-09
NOVEL
UC
.
50
2
231097129
rs6716753
1.98e-17
26192919
CD
SP110,SP140
51
2
234161448
rs6752107
1.42e-73
FM
IBD
ATG16L1
52
2
241574401
rs4676408
2.59e-30
FM
IBD,UC
GPR35
53
2
242484701
rs76527535
2.87e-08
NOVEL
IBD
.
54
2
242737341
rs35320439
1.73e-05
26192919
IBD
GAL3ST2
55
3
18767404
rs4256159
9e-15
23128233
CD
.
56
3
46457412
rs113010081
4.21e-08
26192919
IBD
CCR1,CCRL2,CCR5,CCR3,CCR2
57
3
49721532
rs3197999
1.55e-52
26192919
IBD
TMA7,TREX1,UCN2,TMEM89,SLC26A6,WDR6,NDUFAF3,IMPDH2,KLHDC8B,RP11-3B7.1,C3orf62,GPX1,TCTA,AMT,APEH,PLXNB1,CCDC51,SHISA5,PFKFB4,UQCRC1,CELSR3,NCKIPSD,PRKAR2A,SLC25A20,ARIH2OS,P4HTM,DALRD3,QRICH1,QARS,LAMB2,CCDC71,C3orf84,USP4,NICN1,MST1,RNF123,ATRIP,COL7A1,I
58
3
53062661
rs9847710
1e-08
23128233
UC
RFT1,SFMBT1,RP11-894J14.5
59
3
53133149
rs2581828
6.46e-09
NOVEL
CD
RFT1,RP11-894J14.5
60
3
71175495
rs2593855
2.54e-09
NOVEL
IBD
FOXP1
61
3
101023748
rs503734
2.67e-08
NOVEL
IBD
IMPG2,SENP7
62
3
101569726
rs616597
9.34e-06
26192919
UC
NFKBIZ
63
3
141105570
rs724016
3.36e-06
26192919
CD
ZBTB38
64
3
188401160
rs56116661
5.67e-10
NOVEL
CD
LPP
65
4
3444503
rs2073505
1.46e-07
26192919
IBD
HGFAC
66
4
26132361
rs4692386
1.21e-08
26192919
IBD
.
67
4
38325036
rs6856616
4e-14
23850713
IBD
.
68
4
38588453
rs11734570
4.8e-08
NOVEL
IBD
.
69
4
48363245
rs7438704
3.42e-11
26192919
CD
SLAIN2
70
4
74857708
rs2472649
3e-08
23128233
IBD
PF4,PPBP,CXCL5
71
4
102865304
rs13126505
1.57e-14
26192919
CD,UC
NFKB1,SLC39A8,BANK1
72
4
106075498
rs2189234
1.95e-10
26192919
UC
TET2
73
4
123351431
rs1479918
1.07e-13
FM
IBD
IL2,IL21,KIAA1109,ADAD1
74
5
583442
rs4957048
1e-09
20228799
UC
AC026740.1,TPPP,SLC9A3,CEP72
75
5
10695526
rs2930047
9.78e-14
26192919
IBD
DAP
76
5
35876274
rs3194051
4e-08
21297633
UC
IL7R,CAPSL
77
5
38867732
rs395157
2.22e-20
26192919
IBD
OSMR
78
5
40410584
rs11742570
2e-82
23128233
IBD
.
79
5
55438851
rs10065637
4e-12
23128233
IBD
ANKRD55
80
5
71693899
rs4703855
7.16e-11
26192919
IBD
.
81
5
72539850
rs34804116
1.21e-12
FM
CD
.
82
5
96252803
rs1363907
4.87e-15
26192919
IBD
ERAP2,CTD-2260A17.2,LNPEP
83
5
101946798
rs7705924
2e-08
22412388
CD
SLCO4C1,SLCO6A1
84
5
130017287
rs4836519
4e-10
23128233
IBD
.
85
5
131770805
rs2188962
9.53e-53
FM
IBD
IL3,CSF2,HINT1,LYRM7,SLC22A4,C5orf56,IRF1,CDC42SE2,RAPGEF6,ACSL6,P4HA2,PDLIM4,SLC22A5,CTC-432M15.3,FNIP1
86
5
134443606
rs254560
8.55e-10
26192919
IBD
C5orf66
87
5
141513204
rs6863411
2.41e-14
26192919
IBD
NDFIP1
88
5
149605994
rs17656349
1.54e-08
NOVEL
UC
SLC6A7,CAMK2A
89
5
150277909
rs11741861
3e-37
23128233
IBD
RPS14,TCOF1,CD74,NDST1,SYNPO,MYOZ3,DCTN4,SMIM3,AC010441.1,IRGM,ZNF300,GPX3,ANXA6,SLC36A3,SLC36A2,RBM22,TNIP1,CCDC69,GM2A
90
5
158827769
rs56167332
7.17e-50
26192919
IBD
UBLCP1,IL12B
91
5
172324978
rs564349
1.54e-07
26192919
IBD
ERGIC1
92
5
173279842
rs359457
3e-12
21102463
IBD
CPEB4
93
5
176788570
rs4976646
3.23e-12
26192919
IBD
RGS14,SLC34A1
94
6
382559
rs7773324
5.84e-09
26192919
IBD
.
95
6
3433318
rs17309827
7e-09
21102463
IBD
SLC22A23
96
6
14719496
rs17119
2.18e-11
26192919
IBD
.
97
6
19781009
rs113986290
7.59e-09
NOVEL
UC
.
98
6
20812588
rs9358372
9e-14
23128233
CD
CDKAL1
99
6
21430730
rs71559680
1.78e-15
26192919
CD
.
100
6
32612397
rs6927022
5e-133
23128233
IBD
C6orf15,CDSN,PSORS1C2,HCG27,HLA-C,HLA-B,MCCD1,ATP6V1G2,LTA,TNF,LTB,NCR3,AIF1,BAG6,C6orf47,GPANK1,LY6G5B,LY6G5C,LY6G6F,MEGT1,LY6G6E,LY6G6D,DDAH2,SAPCD1,HSPA1L,HSPA1B,C6orf48,NEU1,ZBTB12,NELFE,DXO,AL645922.1,CYP21A2,FKBPL,PRRT1,EGFL8,RNF5,AGER,PBX2,HLA-DRA,
101
6
42007403
rs67289879
3.04e-08
NOVEL
IBD
CCND3
102
6
43795968
rs943072
2e-10
21297633
UC
.
103
6
90973159
rs1847472
2e-10
23128233
IBD
BACH2
104
6
106435269
rs7746082
1.29e-20
26192919
IBD
.
105
6
111848191
rs3851228
1.5e-15
26192919
IBD
KIAA1919,TRAF3IP2,SLC16A10,REV3L,FYN
106
6
116768917
rs2858829
8e-10
25082827
UC
FAM26F,TRAPPC3L
107
6
127456122
rs9491697
4e-10
23128233
CD
RSPO3
108
6
128277151
rs9491891
9.39e-17
FM
CD
THEMIS,PTPRK
109
6
138006504
rs6920220
1e-21
23128233
IBD
.
110
6
143898894
rs12199775
2e-08
23128233
IBD
PHACTR2
111
6
149577079
rs7758080
1.15e-07
26192919
IBD
TAB2
112
6
159490436
rs212388
1.8e-16
26192919
CD
.
113
6
167373547
rs1819333
7e-21
23128233
IBD
RP11-514O12.4,RNASET2,FGFR1OP,CCR6
114
7
2789880
rs798502
6e-17
23128233
IBD
AMZ1,GNA12
115
7
6545188
rs11768365
3.88e-08
NOVEL
IBD
FLJ20306,DAGLB,KDELR2,GRID2IP
116
7
17442679
rs1077773
5.96e-09
26192919
UC
.
117
7
20577298
rs149169037
3.26e-08
NOVEL
IBD
.
118
7
26892440
rs10486483
1.55e-11
26192919
CD,UC
HOXA1,HOXA2,HOXA4,HOXA6,HOXA9,HOXA11,HOXA13,HOXA3,HOXA5,HOXA7,RP1-170O19.20,HOXA10,SKAP2
119
7
28190730
rs56691573
2.22e-12
FM
CD
JAZF1
120
7
50304461
rs1456896
7e-15
23128233
IBD
C7orf72,ZPBP
121
7
98759117
rs9297145
8e-12
23128233
IBD
KPNA7,SMURF1
122
7
100315517
rs1734907
2e-13
23128233
IBD
GNB2,POP7,TFR2,ACTL6B,GIGYF1,EPO,SLC12A9,EPHB4
123
7
107480315
rs4380874
2e-26
23128233
UC
SLC26A3,DLD,LAMB1
124
7
116892846
rs38904
1e-08
23128233
UC
WNT2
125
7
128573967
rs4728142
1.92e-14
26192919
UC
IRF5
126
7
148220448
rs2538470
3e-11
26192919
IBD
.
127
7
148435339
rs243505
3.04e-10
NOVEL
IBD
CUL1,EZH2
128
8
27227554
rs17057051
5.5e-08
26192919
IBD
PTK2B
129
8
49129242
rs7011507
2.03e-08
26192919
IBD
.
130
8
74007347
rs12677663
2e-08
22412388
CD
SBSPON
131
8
90875918
rs7015630
1e-08
23128233
IBD
.
132
8
126534671
rs921720
8e-20
23128233
IBD
.
133
8
129567181
rs6651252
4e-18
21102463
IBD
.
134
8
130624105
rs1991866
2e-09
23128233
IBD
.
135
9
4981601
rs75900472
4.7e-48
26192919
IBD
.
136
9
34736158
rs9408254
1.95e-08
26974007
CD
CCL21,FAM205A
137
9
93928416
rs4743820
3.8e-09
26192919
IBD
AUH
138
9
117545666
rs6478106
5e-46
23266558
IBD
TNFSF15,TNFSF8
139
9
120475302
rs4986790
6.99e-09
26974007
CD
TLR4
140
9
139266405
rs10781499
4e-56
23128233
IBD
C9orf69,LHX3,DKFZP434A062,DNLZ,UBAC1,QSOX2,GPSM1,CARD9,SNAPC4,SDCCAG3,PMPCA,SEC16A,C9orf163,NOTCH1,NACC2,INPP5E
141
10
6094697
rs61839660
1.24e-14
FM
IBD
DKFZP667F0711,IL2RA,RBM17,PFKFB3,PRKCQ
142
10
27179596
rs7911117
1.84e-08
NOVEL
UC
.
143
10
30728101
rs1042058
6e-11
23128233
IBD
MAP3K8
144
10
35466185
rs34779708
2.39e-26
FM
IBD
CUL2,CREM,CCNY
145
10
59913151
rs1819658
9e-17
21102463
IBD
IPMK,CISD1
146
10
64445564
rs10761659
4.97e-53
26192919
IBD
ADO,ZNF365
147
10
75673101
rs2227564
7e-10
23128233
IBD
AC022400.2,FUT11,CHCHD1,PLAU,SEC24C,ZSWIM8,RP11-574K11.31,NDST2,C10orf55,CAMK2G
148
10
81060317
rs1250550
1e-30
21102463
IBD
ZMIZ1
149
10
82254047
rs6586030
9e-16
23128233
IBD
TSPAN14,SH2D4B
150
10
94436851
rs7911264
3e-08
23128233
IBD
HHEX,IDE,KIF11
151
10
101284237
rs4409764
1.16e-61
26192919
IBD
NKX2-3
152
10
104232716
rs3740415
1.03e-07
26192919
IBD
TMEM180,ACTR1A,SUFU
153
10
112186148
rs11195128
2e-10
23850713
CD
.
154
10
126439381
rs111456533
1.18e-09
NOVEL
IBD
METTL10,FAM175B,RP11-12J10.3,FAM53B
155
10
133172119
rs10734105
3e-08
22412388
CD
.
156
11
1874072
rs907611
1e-10
21297633
IBD
LSP1
157
11
57203009
rs11229030
8e-09
22412388
CD
RP11-872D17.8,SLC43A3
158
11
58408687
rs11229555
5.23e-12
26192919
IBD
OR5B2,OR5B12,OR5B21,AP001350.1,ZFP91,ZFP91-CNTF,CNTF,LPXN,GLYAT
159
11
60776209
rs11230563
1.71e-14
26192919
IBD
CD6
160
11
61564299
rs4246215
2e-15
23128233
IBD
FEN1,MYRF,TMEM258,FADS1,FADS2
161
11
64150370
rs559928
3.33e-13
26192919
IBD
TRPT1,DNAJC4,VEGFB,FKBP2,TEX40,TRMT112,PRDX5,FERMT3,NUDT22,PPP1R14B,PLCB3,BAD,GPR137,KCNK4,ESRRA,CCDC88B,RPS6KA4,STIP1
162
11
65656564
rs2231884
3e-10
23128233
CD
FIBP,CCDC85B,CFL1,SNX32,MUS81,EFEMP2,CTSW,FOSL1
163
11
72863697
rs11235667
7e-09
23850713
CD
.
164
11
76299649
rs11236797
2.25e-50
FM
IBD
.
165
11
87125438
rs6592362
2e-08
23128233
IBD
.
166
11
96023427
rs483905
3.16e-10
26192919
UC
MAML2
167
11
114397162
rs200349593
3.56e-20
FM
UC
RBM7,REXO2,NXPE4,NXPE1,RP11-212D19.4
168
11
118754353
rs630923
7e-09
23128233
CD
.
169
11
128380974
rs11221332
2.44e-09
26974007
IBD
ETS1
图文展示
ID
Chr
Position (bp)
SNP
P value
Study (PMID)
Phenotype
Genes in locus
170
12
6491125
rs7954567
1.3e-09
26192919
CD
LTBR
171
12
12657513
rs11612508
1e-08
23128233
UC
DUSP16,LOH12CR1
172
12
40740223
rs148319899
5.54e-29
FM
IBD
SLC2A13,LRRK2,MUC19
173
12
48208368
rs11168249
8e-09
23128233
UC
HDAC7
174
12
68508122
rs11614178
2.22e-32
FM
IBD
.
175
12
112007756
rs653178
1.11e-08
26192919
IBD
SH2B3,BRAP,ACAD10,ALDH2,TMEM116,NAA25,ATXN2,MAPKAPK5,ERP29,RP11-162P23.2
176
12
120146925
rs11064881
5.95e-08
26192919
IBD
RP1-127H14.3,PRKAB1,CIT
177
13
27531267
rs17085007
3e-19
23128233
UC
.
178
13
41013977
rs941823
2e-14
23128233
IBD
.
179
13
41558110
rs7329174
8e-09
23266558
CD
KBTBD6,KBTBD7,WBP4,ELF1
180
13
42917861
rs80244186
3.66e-08
NOVEL
CD
AKAP11
181
13
43052880
rs2062305
5e-10
21102463
CD
.
182
13
44457925
rs3764147
2e-21
23128233
IBD
LACC1,CCDC122
183
13
49595331
rs2026029
9.73e-09
26974007
CD
MLNR,FNDC3A
184
13
99956622
rs9557195
2e-14
23128233
IBD
GPR18,GPR183,UBAC2
185
14
69210199
rs4902642
2e-10
21102463
IBD
ZFP36L1
186
14
75741751
rs1569328
3.21e-09
26192919
IBD
FOS,RP11-293M10.1
187
14
88472595
rs8005161
4e-18
21102463
IBD
GALC,GPR65
188
15
38899190
rs16967103
4e-09
23128233
IBD
RASGRP1
189
15
41563950
rs28374715
2e-08
23128233
UC
EXD1,OIP5,NUSAP1,RTF1,INO80,CHP1,NDUFAF1
190
15
67442596
rs17293632
2.71e-20
26192919
IBD
SMAD3
191
15
91172901
rs7495132
9e-11
23128233
IBD
CRTC3
192
16
11373320
rs529866
2e-16
23128233
CD
SOCS1,TNP2,PRM3,PRM2,PRM1,RMI2,LITAF,CTD-3088G3.8
193
16
23864590
rs7404095
1e-09
23128233
IBD
PRKCB
194
16
28528781
rs28449958
7.5e-24
FM
IBD
IL27,NUPR1,TUFM,NPIPB6,EIF3CL,NPIPB7,CLN3,CLN3,APOBR,SULT1A2,SULT1A1,NPIPB8,NPIPB9,SH2B1,ATP2A1,RABEP2,CD19,CCDC101,EIF3C,ATXN2L
195
16
30482494
rs11150589
1.63e-11
FM
UC
ITGAL
196
16
50335074
rs78534766
1.17e-14
NOVEL* (Luo et al, In Press)
UC
ADCY7
197
16
50745926
rs2066844
2.27e-217
FM
IBD
SNX20,NOD2,CYLD,NKD1
198
16
68591230
rs1728785
3e-08
19915572
UC
ZFP90,CDH3
199
16
81916912
rs11548656
5.18e-11
NOVEL
IBD
PLCG2
200
16
82867456
rs10492862
1.26e-09
NOVEL
CD
CDH13
201
16
86014241
rs16940202
6e-19
21297633
IBD
.
202
17
25869033
rs10775412
2.51e-25
FM
CD
KSR1
203
17
32593974
rs3091316
1e-26
23128233
IBD
AC005549.3,CCL2,CCL7,CCL11
204
17
37912377
rs12946510
2.16e-39
26192919
IBD
GSDMB,ORMDL3,LRRC3C,GRB7,ZPBP2,GSDMA,IKZF3
205
17
40527544
rs12942547
6e-22
23128233
IBD
NAGLU,STAT5A,PTRF,STAT5B,STAT3,ATP6V0A1
206
17
54880993
rs3853824
7.7e-10
26192919
IBD
C17orf67,DGKE
207
17
57963537
rs1292053
9e-13
23128233
IBD
TUBD1,RPS6KB1,RP11-178C3.1,RNFT1,VMP1
208
17
70642923
rs17780256
3.19e-11
26192919
IBD
SLC39A11
209
17
76737118
rs17736589
4.34e-08
26192919
UC
CYTH1,USP36
210
18
12818922
rs80262450
3.97e-28
FM
IBD
PTPN2
211
18
46395022
rs7240004
1.01e-10
26192919
IBD
.
212
18
56879827
rs9319943
9.05e-07
26192919
CD
.
213
18
67530439
rs727088
5e-09
23128233
IBD
CD226,DOK6
214
18
77220616
rs7236492
1.45e-08
26192919
IBD
NFATC1
215
19
1124031
rs2024092
8e-22
23128233
IBD
GPX4,SBNO2,STK11
216
19
10512911
rs11879191
5.27e-20
26192919
IBD
CTD-2369P2.12,ICAM3,ZGLP1,CTD-2369P2.10,FDX1L,RAVER1,CDC37,PDE4A,KEAP1,TYK2
217
19
33731551
rs17694108
6e-15
23128233
IBD
.
218
19
34656406
rs587259
2.98e-08
26974007
CD
LSM14A
219
19
46849806
rs4802307
9.04e-12
26192919
CD,UC
CCDC8,PNMAL2,AC011484.1,CALM3,PTGIR,GNG8,PPP5C,PNMAL1,PPP5D1,AC011551.3
220
19
49206172
rs516246
1.33e-20
26192919
CD
IZUMO1,NTN5,FUT2,MAMSTR,RASIP1
221
19
55383051
rs11672983
7e-11
23128233
IBD
KIR3DL2,FCAR,KIR3DL1
222
20
6093889
rs4256018
1.23e-08
NOVEL
IBD
FERMT1
223
20
30725648
rs6142618
6e-10
23128233
IBD
TM9SF4,PLAGL2,KIF3B,ASXL1,POFUT1,C20orf112
224
20
31376282
rs4911259
1e-09
23128233
IBD
DNMT3B,MAPRE1,COMMD7,EFCAB8
225
20
33799280
rs6088765
2e-08
23128233
IBD
EIF6,FAM83C,EDEM2,MMP24
226
20
43065028
rs6017342
5.17e-50
FM
UC
C20orf62,SERINC3,PKIG,Z97053.1,TTPAL,ADA
227
20
44742064
rs1569723
1e-13
23128233
IBD
CD40,SLC12A5,NCOA5
228
20
48955424
rs913678
5.35e-11
26192919
IBD
.
229
20
57824309
rs259964
1e-12
23128233
IBD
ZNF831
230
20
62329099
rs6062496
6.76e-26
FM
IBD
TNFRSF6B,ARFRP1,LIME1,RP4-583P15.14,STMN3,RTEL1,RTEL1-TNFRSF6B,ZGPAT,RP4-583P15.15,SLC2A4RG,ZBTB46
231
21
16817938
rs2823286
9e-30
23128233
IBD
.
232
21
34776695
rs2284553
5.63e-17
26192919
CD
IFNGR2
233
21
40465534
rs2836878
5e-48
23128233
IBD
.
234
21
45615741
rs7282490
9.85e-30
26192919
IBD
.
235
22
21922904
rs2266959
1e-16
23128233
IBD
YDJC,SDF2L1,UBE2L3,CCDC116
236
22
30493882
rs5763767
8.82e-15
26192919
IBD
UQCR10,ASCC2,ZMAT5,HORMAD2,MTMR3
237
22
35729721
rs138788
2.95e-08
NOVEL
UC
TOM1
238
22
37258503
rs4821544
1.76e-08
NOVEL
CD
NCF4
239
22
39659773
rs2413583
5.06e-38
26192919
IBD
SYNGR1,RPL3
240
22
41867377
rs727563
1.88e-10
26192919
CD
DNAJB7,AL035681.1,TOB2,ST13,RBX1,L3MBTL2,CHADL,ZC3H7B,TEF,PHF5A,ACO2,POLR3H,CSDC2,PMM1,DESI1,XRCC6,C22orf46,MEI1,XPNPEP3,EP300,RANGAP1,NHP2L1,CCDC134
241
22
50435480
rs5771069
4e-08
20228798
UC
PIM3,IL17REL,TTLL8



Ref:de Lange KM, Moutsianas L, Lee JC, et al. Genome-wide association study implicates immune activation of multiple integrin genes in   inflammatory bowel disease. Nat Genet. 2017 Feb;49(2):256-261. doi: 10.1038/ng.3760 Epub 2017 Jan 9. PMID: 28067908 PMCID: PMC5289481

IBD associated SNPs

Chr
Position (hg19 (Mb))
SNP
Key Genes
p-value
OR
Crohn's Disease
1
78.62
rs17391694
(5)
2.96E-09
1.134
1
114.3
rs6679677§
PTPN22,DCLRE1B,(7)
2.03E-15
1.196^
1
120.45
rs3897478
ADAM30,(5)
1.97E-11
1.161
1
172.85
rs9286879
FASLG,TNFSF18,(0)
5.53E-22
1.125
2
27.63
rs1728918
UCN,(23)
4.86E-16
1.123
2
62.55
rs10865331
(3)
9.77E-10
1.098
2
231.09
rs6716753
SP140,(5)
1.17E-16
1.134
2
234.145
rs12994997
ATG16L1, INPP5D, (7)
4.14E-70
1.233
4
48.36
rs6837335
TXK,TEC,SLC10A4,(3)
1.75E-08
1.086
4
102.86
rs13126505
(1)
1.84E-12
1.172
5
55.43
rs10065637
IL6ST,IL31RA,(1)
3.68E-12
1.123
5
72.54
rs7702331
(4)
5.63E-10
1.088
5
173.34
rs17695092
CPEB4,(2)
4.68E-09
1.095
6
21.42
rs12663356
(3)
4.01E-12
1.095
6
31.27
rs9264942
HLA-C,PSORS1C1,NFKBIL1,MICB,(18)
4.96E-28
1.145
6
127.45
rs9491697
(3)
3.79E-10
1.077
6
128.24
rs13204742
(2)
8.38E-15
1.173
6
159.49
rs212388
TAGAP,(5)
3.04E-14
1.105
7
26.88‡
rs10486483
(2)
3.48E-08
1.089
7
28.17
rs864745
CREB5,JAZF1,(1)
3.65E-09
1.087
8
90.87
rs7015630
RIPK2,(4)
1.42E-08
1.075
8
129.56
rs6651252
(0)
1.45E-16
1.185
13
44.45
rs3764147
LACC1,(3)
2.19E-21
1.155
15
38.89
rs16967103
RASGRP1,SPRED1,(2)
3.88E-09
1.088
16
50.66**
rs2066847§
NOD2,ADCY7,(5)
               5.86E-209
3.103^
17
25.84
rs2945412
LGALS9,NOS2,(3)
8.68E-17
1.137
19
1.12
rs2024092
GPX4,HMHA1,(20)
8.26E-22
1.156
19
46.85‡
rs4802307
(9)
2.00E-10
1.099
19
49.2
rs516246
DBP,SPHK2,IZUMO1,FUT2,(22)
1.00E-15
1.107
21
34.77
rs2284553
IFNGR2,IFNAR1,IFNAR2,IL10RB,GART,TMEM50B,(6)
2.14E-16
1.123
Ulcerative Colitis
1
2.5
rs10797432
TNFRSF14,MMEL1,PLCH2,(8)
2.62E-12
1.078
1
20.15**
rs6426833
(9)
2.39E-68
1.265
1
200.09
rs2816958
(3)
1.98E-17
1.23
2
198.65
rs1016883
RFTN2,PLCL1,(7)
2.87E-08
1.1
2
199.70*
rs17229285
(0)
1.73E-13
1.117
3
53.05
rs9847710
PRKCD,ITIH4,(8)
1.05E-08
1.064
4
103.51
rs3774959
NFKB1,MANBA,(2)
3.66E-12
1.118
5
0.59
rs11739663
SLC9A3,(8)
1.81E-08
1.071
5
134.44
rs254560
(6)
2.55E-09
1.056
6
32.595
rs6927022
HLA-DQB1,HLA-DRB1,HLA-DQA1,HLA-DRA,(12)
               4.71E-133
1.444
7
2.78
rs798502
CARD11,GNA12,TTYH3,(4)
6.09E-17
1.127
7
27.22‡
rs4722672
(14)
2.06E-08
1.091
7
107.45*
rs4380874
DLD,(9)
2.07E-26
1.137
7
128.57
rs4728142
IRF5,TNPO3,TSPAN33,(11)
4.37E-14
1.104
11
96.02
rs483905
JRKL,MAML2,(2)
1.21E-08
1.056
11
114.38
rs561722
FAM55A,FAM55D,(5)
5.15E-17
1.12
15
41.55
rs28374715
ITPKA,NDUFAF1,NUSAP1,(8)
2.43E-08
1.082
16
30.47
rs11150589
ITGAL,(20)
6.04E-10
1.09
16
68.58
rs1728785
ZFP90,(6)
3.71E-08
1.075
17
70.64
rs7210086
(3)
1.89E-09
1.111
19
47.12‡
rs1126510
CALM3,(14)
1.55E-09
1.075
20
33.8
rs6088765
PROCR,UQCC,CEP250,(8)
2.21E-08
1.079
20
43.06
rs6017342
ADA,HNF4A,(9)
1.43E-43
1.228
Inflammatory Bowel Disease
1
1.24
rs12103
TNFRSF18,TNFRSF4,(30)
7.66E-13
1.099
1
8.02
rs35675666
TNFRSF9,(6)
1.12E-15
1.112
1
22.7
rs12568930†
(3)
1.26E-17
1.095
1
67.68**
rs11209026†
IL23R,IL12RB2,(4)
               8.12E-161
2.013
1
70.99
rs2651244†
(3)
2.29E-08
1.015
1
151.79
rs4845604†
RORC,(14)
3.52E-16
1.144
1
155.67
rs670523†
UBQLN4,RIT1,MSTO1,(28)
5.79E-11
1.06
1
160.85
rs4656958†
CD48,SLAMF1,ITLN1,CD244,F11R,USF1,SLAMF7,ARHGAP30,(8)
6.80E-09
1.061
1
161.47
rs1801274†
FCGR2A,FCGR2B,FCGR3A,HSPA6,FCGR3B,FCRLA,(9)
2.12E-38
1.124
1
197.6
rs2488389
C1orf53,(2)
8.45E-13
1.115
1
200.87
rs7554511
KIF21B,(6)
1.24E-32
1.164
1
206.93
rs3024505†
IL10,IL20,IL19,IL24,PIGR,MAPKAPK2,FAIM3,RASSF5,(3)
6.66E-42
1.208
2
25.12
rs6545800†
ADCY3,(6)
6.14E-16
1.109
2
28.61
rs925255†
FOSL2,BRE,(1)
2.67E-15
1.092
2
43.81
rs10495903†
(5)
8.03E-12
1.086
2
61.2
rs7608910
REL,C2orf74,KIAA1841,AHSA2,(6)
8.65E-32
1.138
2
65.67
rs6740462
SPRED2,(1)
2.35E-08
1.081
2
102.86*
rs917997†
IL1R2,IL18RAP,IL18R1,IL1R1,IL1RL1,IL1RL2,(3)
3.12E-20
1.103
2
163.1
rs2111485
IFIH1,(5)
1.93E-08
1.066
2
191.92
rs1517352
STAT1,STAT4,(2)
3.28E-11
1.077
2
219.14
rs2382817
SLC11A1,CXCR2,CXCR1,PNKD,ARPC2,TMBIM1,CTDSP1,(8)
3.70E-12
1.073
2
241.57*
rs3749171†
GPR35,(12)
3.07E-21
1.135
3
18.76
rs4256159†
(0)
9.00E-15
1.107
3
48.96**
rs3197999
MST1,PFKFB4,MST1R,UCN2,GPX1,IP6K2,BSN,IP6K1,USP4,(56)
1.01E-47
1.18
4
74.85
rs2472649†
CXCL5,CXCL1,CXCL3,IL8,CXCL6,PF4,CXCL2,PF4V1,(3)
2.57E-08
1.095
4
123.22
rs7657746
IL2,IL21,(2)
2.76E-13
1.116
5
10.69
rs2930047
DAP,(2)
1.03E-08
1.065
5
40.38**
rs11742570†
PTGER4,(1)
1.81E-82
1.198
5
96.24
rs1363907
ERAP2,ERAP1,LNPEP,(2)
5.62E-13
1.068
5
130.005
rs4836519†
(1)
4.24E-10
1.072
5
131.19*
rs2188962†
IRF1,IL13,CSF2,SLC22A4,IL4,IL3,IL5,PDLIM4,SLC22A5,ACSL6,(8)
1.35E-52
1.158
5
141.51
rs6863411†
SPRY4,NDFIP1,(5)
3.59E-14
1.089
5
150.27
rs11741861†
TNIP1,IRGM,ZNF300P1,(8)
2.94E-37
1.249
5
158.8**
rs6871626†
IL12B,(3)
1.43E-42
1.181
5
176.79
rs12654812
DOK3,(17)
1.68E-08
1.068
6
14.71
rs17119
(0)
3.08E-11
1.071
6
20.77*
rs9358372†
(2)
8.66E-14
1.089
6
90.96
rs1847472
(1)
1.57E-10
1.06
6
106.43
rs6568421†
(2)
8.24E-20
1.108
6
111.82
rs3851228
TRAF3IP2,FYN,REV3L,(2)
1.08E-13
1.153
6
138
rs6920220†
TNFAIP3,(1)
1.40E-21
1.102
6
143.9
rs12199775
PHACTR2,(5)
1.99E-08
1.129
6
167.37
rs1819333†
CCR6,RPS6KA2,RNASET2,(3)
6.76E-21
1.081
7
50.245*
rs1456896
ZPBP,IKZF1,(4)
7.28E-15
1.088
7
98.75
rs9297145
SMURF1,(6)
8.21E-12
1.082
7
100.335
rs1734907†
EPO,(21)
1.67E-13
1.114
7
116.89
rs38904†
(6)
1.31E-08
1.054
8
126.53
rs921720†
TRIB1,(1)
8.30E-20
1.081
8
130.62
rs1991866
(2)
1.65E-09
1.054
9
4.98
rs10758669
JAK2,(4)
7.88E-45
1.174
9
93.92
rs4743820†
NFIL3,(2)
3.60E-09
1.056
9
117.60**
rs4246905
TNFSF8,TNFSF15,TNC,(2)
2.80E-32
1.142
9
139.32*
rs10781499†
CARD9,PMPCA,SDCCAG3,INPP5E,(19)
4.38E-56
1.188
10
6.08
rs12722515†
IL2RA,IL15RA,(6)
3.76E-10
1.102
10
30.72
rs1042058†
MAP3K8,(3)
5.93E-11
1.075
10